Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle

Proteasomes occur in all three domains of life, and are the principal molecular machines for the regulated degradation of intracellular proteins. They play key roles in the maintenance of protein homeostasis, and control vital cellular processes. While the eukaryotic 26S proteasome is extensively ch...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Majumder, Parijat, Rudack, Till, Beck, Florian, Danev, Radostin, Pfeifer, Günter, Nagy, István, Baumeister, Wolfgang
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2019
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329974/
https://ncbi.nlm.nih.gov/pubmed/30559193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817752116
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