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Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle

Proteasomes occur in all three domains of life, and are the principal molecular machines for the regulated degradation of intracellular proteins. They play key roles in the maintenance of protein homeostasis, and control vital cellular processes. While the eukaryotic 26S proteasome is extensively ch...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Majumder, Parijat, Rudack, Till, Beck, Florian, Danev, Radostin, Pfeifer, Günter, Nagy, István, Baumeister, Wolfgang
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329974/
https://ncbi.nlm.nih.gov/pubmed/30559193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817752116
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