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Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis
Nonalcoholic fatty liver disease (NAFLD) is characterized by abnormal accumulation of triglycerides (TG) in the liver and other metabolic syndrome symptoms, but its molecular genetic causes are not completely understood. Here, we show that mice deficient for ubiquitin ligase (E3) Smad ubiquitin regu...
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| Publicat a: | PLoS Biol |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6317813/ https://ncbi.nlm.nih.gov/pubmed/30566427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000091 |
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