Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis

Nonalcoholic fatty liver disease (NAFLD) is characterized by abnormal accumulation of triglycerides (TG) in the liver and other metabolic syndrome symptoms, but its molecular genetic causes are not completely understood. Here, we show that mice deficient for ubiquitin ligase (E3) Smad ubiquitin regu...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Biol
Main Authors: Zhu, Kun, Tang, Yi, Xu, Xuan, Dang, Hien, Tang, Liu-Ya, Wang, Xiang, Wang, Xin Wei, Zhang, Ying E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6317813/
https://ncbi.nlm.nih.gov/pubmed/30566427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000091
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki