Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice

Peroxisome proliferator-activated receptor γ (PPARγ) is the target for thiazolidinones (TZDs), drugs that improve insulin sensitivity and fatty liver in humans and rodent models, related to a reduction in hepatic de novo lipogenesis (DNL). The systemic effects of TZDs are in contrast to reports sugg...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Greenstein, Abigail Wolf, Majumdar, Neena, Yang, Peng, Subbaiah, Papasani V., Kineman, Rhonda D., Cordoba-Chacon, Jose
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120553/
https://ncbi.nlm.nih.gov/pubmed/27799461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0447
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados