Adult-Onset Hepatocyte GH Resistance Promotes NASH in Male Mice, Without Severe Systemic Metabolic Dysfunction

Nonalcoholic fatty liver disease (NAFLD), which includes nonalcoholic steatohepatitis (NASH), is associated with reduced GH input/signaling, and GH therapy is effective in the reduction/resolution of NAFLD/NASH in selected patient populations. Our laboratory has focused on isolating the direct vs in...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Cordoba-Chacon, Jose, Sarmento-Cabral, Andre, del Rio-Moreno, Mercedes, Diaz-Ruiz, Alberto, Subbaiah, Papasani V, Kineman, Rhonda D
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202859/
https://ncbi.nlm.nih.gov/pubmed/30295789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00669
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