Hepatic PPARγ Is Not Essential for the Rapid Development of Steatosis After Loss of Hepatic GH Signaling, in Adult Male Mice

Our group has previously reported de novo lipogenesis (DNL) and hepatic triglyceride content increases in chow-fed male mice within 7 days of hepatocyte-specific GH receptor knockdown (aLivGHRkd). Here, we report that these changes are associated with an increase in hepatic expression of peroxisome...

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Bibliografiska uppgifter
I publikationen:Endocrinology
Huvudupphovsmän: Kineman, Rhonda D., Majumdar, Neena, Subbaiah, Papasani V., Cordoba-Chacon, Jose
Materialtyp: Artigo
Språk:Inglês
Publicerad: Endocrine Society 2016
Ämnen:
Brief Research Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870866/
https://ncbi.nlm.nih.gov/pubmed/26950202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2077
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