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Hepatic PPARγ Is Not Essential for the Rapid Development of Steatosis After Loss of Hepatic GH Signaling, in Adult Male Mice

Our group has previously reported de novo lipogenesis (DNL) and hepatic triglyceride content increases in chow-fed male mice within 7 days of hepatocyte-specific GH receptor knockdown (aLivGHRkd). Here, we report that these changes are associated with an increase in hepatic expression of peroxisome...

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Publicat a:Endocrinology
Autors principals: Kineman, Rhonda D., Majumdar, Neena, Subbaiah, Papasani V., Cordoba-Chacon, Jose
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870866/
https://ncbi.nlm.nih.gov/pubmed/26950202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-2077
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