GH directly inhibits steatosis and liver injury in a sex-dependent and IGF1-independent manner

A reduction in hepatocyte growth hormone (GH)-signaling promotes non-alcoholic fatty liver disease (NAFLD). However, debate remains as to the relative contribution of the direct effects of GH on hepatocyte function versus indirect effects, via alterations in insulin-like growth factor 1 (IGF1). To i...

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Detalhes bibliográficos
Publicado no:J Endocrinol
Main Authors: Sarmento-Cabral, Andre, del Rio-Moreno, Mercedes, Vazquez-Borrego, Mari C., Mahmood, Mariyah, Gutierrez-Casado, Elena, Pelke, Natalie, Guzman, Grace, Subbaiah, Papasani V., Cordoba-Chacon, Jose, Yakar, Shoshana, Kineman, Rhonda D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785648/
https://ncbi.nlm.nih.gov/pubmed/33112796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-20-0326
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