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Hepatocyte-specific, PPARγ-regulated mechanisms to promote steatosis in adult mice
Peroxisome proliferator-activated receptor γ (PPARγ) is the target for thiazolidinones (TZDs), drugs that improve insulin sensitivity and fatty liver in humans and rodent models, related to a reduction in hepatic de novo lipogenesis (DNL). The systemic effects of TZDs are in contrast to reports sugg...
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| Pubblicato in: | J Endocrinol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120553/ https://ncbi.nlm.nih.gov/pubmed/27799461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-16-0447 |
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