Ubiquitination of Tumor Necrosis Factor Receptor-associated Factor 4 (TRAF4) by Smad Ubiquitination Regulatory Factor 1 (Smurf1) Regulates Motility of Breast Epithelial and Cancer Cells

Smad ubiquitin regulatory factors (Smurfs) are HECT-domain ubiquitin E3 ligases that regulate diverse cellular processes, including normal and tumor cell migration. However, the underlying mechanism of the Smurfs' role in cell migration is not fully understood. Here we show that Smurf1 induces...

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Detalhes bibliográficos
Main Authors: Wang, Xiangchun, Jin, Chaoyang, Tang, Yi, Tang, Liu-Ya, Zhang, Ying E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724635/
https://ncbi.nlm.nih.gov/pubmed/23760265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.472704
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