Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3

TGF-β signalling is regulated by post-translational modifications of Smad proteins to translate quantitative difference in ligand concentration into proportional transcriptional output. Previous studies in cell culture systems suggested that Smad ubiquitination regulatory factors (Smurfs) act in thi...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tang, Liu-Ya, Yamashita, Motozo, Coussens, Nathan P, Tang, Yi, Wang, Xiangchun, Li, Cuiling, Deng, Chu-Xia, Cheng, Steven Y, Zhang, Ying E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3243605/
https://ncbi.nlm.nih.gov/pubmed/22045334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.393
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