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Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension

Concentric lung vascular wall thickening due to enhanced proliferation of pulmonary arterial smooth muscle cells is an important pathological cause for the elevated pulmonary vascular resistance reported in patients with pulmonary arterial hypertension. We identified a differential role of mammalian...

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Podrobná bibliografie
Vydáno v:JACC Basic Transl Sci
Hlavní autoři: Tang, Haiyang, Wu, Kang, Wang, Jian, Vinjamuri, Sujana, Gu, Yali, Song, Shanshan, Wang, Ziyi, Zhang, Qian, Balistrieri, Angela, Ayon, Ramon J., Rischard, Franz, Vanderpool, Rebecca, Chen, Jiwang, Zhou, Guofei, Desai, Ankit A., Black, Stephen M., Garcia, Joe G.N., Yuan, Jason X.-J., Makino, Ayako
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314964/
https://ncbi.nlm.nih.gov/pubmed/30623134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.08.009
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