ロード中...
Fenestrations control resting-state block of a voltage-gated sodium channel
Potency of drug action is usually determined by binding to a specific receptor site on target proteins. In contrast to this conventional paradigm, we show here that potency of local anesthetics (LAs) and antiarrhythmic drugs (AADs) that block sodium channels is controlled by fenestrations that allow...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
|---|---|
| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6304959/ https://ncbi.nlm.nih.gov/pubmed/30518562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814928115 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|