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THE CRYSTAL STRUCTURE OF A VOLTAGE-GATED SODIUM CHANNEL
Voltage-gated sodium channels initiate electrical signaling in excitable cells and are the molecular targets for drugs and disease mutations, but the structural basis for their voltage-dependent activation, ion selectivity, and drug block is unknown. Here, we report the crystal structure of a voltag...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266868/ https://ncbi.nlm.nih.gov/pubmed/21743477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10238 |
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