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Structural basis for Ca(2+) selectivity of a voltage-gated calcium channel
Voltage-gated calcium (Ca(V)) channels catalyze rapid, highly selective influx of Ca(2+) into cells despite 70-fold higher extracellular concentration of Na(+). How Ca(V) channels solve this fundamental biophysical problem remains unclear. Here we report physiological and crystallographic analyses o...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2013
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3877713/ https://ncbi.nlm.nih.gov/pubmed/24270805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12775 |
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