Structures of closed and open states of a voltage-gated sodium channel

Bacterial voltage-gated sodium channels (BacNavs) serve as models of their vertebrate counterparts. BacNavs contain conserved voltage-sensing and pore-forming domains, but they are homotetramers of four identical subunits, rather than pseudotetramers of four homologous domains. Here, we present stru...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Lenaeus, Michael J., Gamal El-Din, Tamer M., Ing, Christopher, Ramanadane, Karthik, Pomès, Régis, Zheng, Ning, Catterall, William A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393245/
https://ncbi.nlm.nih.gov/pubmed/28348242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700761114
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