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SIRT2 knockout exacerbates insulin resistance in high fat-fed mice
The NAD(+)-dependent deacetylase SIRT2 is unique amongst sirtuins as it is effective in the cytosol, as well as the mitochondria. Defining the role of cytosolic acetylation state in specific tissues is difficult since even physiological effects at the whole body level are unknown. We hypothesized th...
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| Pubblicato in: | PLoS One |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6289500/ https://ncbi.nlm.nih.gov/pubmed/30533032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208634 |
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