Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice

Insulin resistance due to overnutrition places a burden on energy-producing pathways in skeletal muscle (SkM). Nevertheless, energy state is not compromised. The hypothesis that the energy sensor AMPK is necessary to offset the metabolic burden of overnutrition was tested using chow-fed and high-fat...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Lantier, Louise, Williams, Ashley S., Williams, Ian M., Guerin, Amanda, Bracy, Deanna P., Goelzer, Mickael, Foretz, Marc, Viollet, Benoit, Hughey, Curtis C., Wasserman, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372072/
https://ncbi.nlm.nih.gov/pubmed/32439824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-1074
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