Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice

Insulin resistance due to overnutrition places a burden on energy-producing pathways in skeletal muscle (SkM). Nevertheless, energy state is not compromised. The hypothesis that the energy sensor AMPK is necessary to offset the metabolic burden of overnutrition was tested using chow-fed and high-fat...

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Bibliografske podrobnosti
izdano v:Diabetes
Main Authors: Lantier, Louise, Williams, Ashley S., Williams, Ian M., Guerin, Amanda, Bracy, Deanna P., Goelzer, Mickael, Foretz, Marc, Viollet, Benoit, Hughey, Curtis C., Wasserman, David H.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2020
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7372072/
https://ncbi.nlm.nih.gov/pubmed/32439824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-1074
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