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B cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies
B-cell activation during normal immune responses and oncogenic transformation impose increased metabolic demands on B-cells and their ability to retain redox homeostasis. While the serine/threonine-protein phosphatase 2A (PP2A) was identified as tumor suppressor in multiple types of cancer, our gene...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6284818/ https://ncbi.nlm.nih.gov/pubmed/29551267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.02.048 |
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