Signaling input from divergent pathways subverts B-cell transformation

Malignant transformation typically involves multiple genetic lesions whose combined activity gives rise to cancer1. Our analysis of 1,148 patient-derived B-cell leukemia (B-ALL) samples revealed that individual mutations did not promote leukemogenesis unless they converged on one single oncogenic pa...

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Xehetasun bibliografikoak
Argitaratua izan da:Nature
Egile Nagusiak: Chan, Lai N., Murakami, Mark A., Robinson, Mark E., Caeser, Rebecca, Sadras, Teresa, Lee, Jaewoong, Cosgun, Kadriye Nehir, Kume, Kohei, Khairnar, Vishal, Xiao, Gang, Ahmed, Mohamed A., Aghania, Eamon, Deb, Gauri, Hurtz, Christian, Shojaee, Seyedmehdi, Hong, Chao, Pölönen, Petri, Nix, Matthew A., Chen, Zhengshan, Chen, Chun Wei, Chen, Jianjun, Vogt, Andreas, Heinäniemi, Merja, Lohi, Olli, Wiita, Arun P., Izraeli, Shai, Geng, Huimin, Weinstock, David M., Müschen, Markus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7394729/
https://ncbi.nlm.nih.gov/pubmed/32699415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2513-4
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