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Catalyst free, C-3 Functionalization of Imidazo[1,2-a]pyridines to Rapidly Access New Chemical Space for Drug Discovery Efforts

Multicomoponenet reactions (MCRs) are robust tools for the rapid synthesis of complex, small molecule libraries for use in drug discovery and development. By utilizing MCR chemistry, we developed a protocol to functionalize the C-3 position of imidazo[1,2-a]pyridine through a three component, decarb...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Chem Commun (Camb)
Hauptverfasser: Naresh, Gunaganti, Kharbanda, Anupreet, Lakkaniga, Naga Rajiv, Zhang, Lingtian, Cooper, Rose, Li, Hong-yu, Frett, Brendan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284400/
https://ncbi.nlm.nih.gov/pubmed/30375586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc07063f
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