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Catalyst free, C-3 Functionalization of Imidazo[1,2-a]pyridines to Rapidly Access New Chemical Space for Drug Discovery Efforts

Multicomoponenet reactions (MCRs) are robust tools for the rapid synthesis of complex, small molecule libraries for use in drug discovery and development. By utilizing MCR chemistry, we developed a protocol to functionalize the C-3 position of imidazo[1,2-a]pyridine through a three component, decarb...

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Bibliographic Details
Published in:Chem Commun (Camb)
Main Authors: Naresh, Gunaganti, Kharbanda, Anupreet, Lakkaniga, Naga Rajiv, Zhang, Lingtian, Cooper, Rose, Li, Hong-yu, Frett, Brendan
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284400/
https://ncbi.nlm.nih.gov/pubmed/30375586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc07063f
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