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Catalyst free, C-3 Functionalization of Imidazo[1,2-a]pyridines to Rapidly Access New Chemical Space for Drug Discovery Efforts

Multicomoponenet reactions (MCRs) are robust tools for the rapid synthesis of complex, small molecule libraries for use in drug discovery and development. By utilizing MCR chemistry, we developed a protocol to functionalize the C-3 position of imidazo[1,2-a]pyridine through a three component, decarb...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Naresh, Gunaganti, Kharbanda, Anupreet, Lakkaniga, Naga Rajiv, Zhang, Lingtian, Cooper, Rose, Li, Hong-yu, Frett, Brendan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284400/
https://ncbi.nlm.nih.gov/pubmed/30375586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc07063f
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