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Catalyst free, C-3 Functionalization of Imidazo[1,2-a]pyridines to Rapidly Access New Chemical Space for Drug Discovery Efforts

Multicomoponenet reactions (MCRs) are robust tools for the rapid synthesis of complex, small molecule libraries for use in drug discovery and development. By utilizing MCR chemistry, we developed a protocol to functionalize the C-3 position of imidazo[1,2-a]pyridine through a three component, decarb...

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Podrobná bibliografie
Vydáno v:Chem Commun (Camb)
Hlavní autoři: Naresh, Gunaganti, Kharbanda, Anupreet, Lakkaniga, Naga Rajiv, Zhang, Lingtian, Cooper, Rose, Li, Hong-yu, Frett, Brendan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284400/
https://ncbi.nlm.nih.gov/pubmed/30375586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8cc07063f
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