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Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems

Adverse drug reactions (ADRs) restrict the maximum doses applicable in chemotherapy, which leads to failure in cancer treatment. Various approaches, including nano-drug and prodrug strategies aimed at reducing ADRs, have been developed, but these strategies have their own pitfalls. A renovated strat...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Yao, Qingxin, Lin, Feng, Fan, Xinyuan, Wang, Yanpu, Liu, Ye, Liu, Zhaofei, Jiang, Xingyu, Chen, Peng R., Gao, Yuan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261997/
https://ncbi.nlm.nih.gov/pubmed/30487642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07490-6
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