Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems

Adverse drug reactions (ADRs) restrict the maximum doses applicable in chemotherapy, which leads to failure in cancer treatment. Various approaches, including nano-drug and prodrug strategies aimed at reducing ADRs, have been developed, but these strategies have their own pitfalls. A renovated strat...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Yao, Qingxin, Lin, Feng, Fan, Xinyuan, Wang, Yanpu, Liu, Ye, Liu, Zhaofei, Jiang, Xingyu, Chen, Peng R., Gao, Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261997/
https://ncbi.nlm.nih.gov/pubmed/30487642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07490-6
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