Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems

Adverse drug reactions (ADRs) restrict the maximum doses applicable in chemotherapy, which leads to failure in cancer treatment. Various approaches, including nano-drug and prodrug strategies aimed at reducing ADRs, have been developed, but these strategies have their own pitfalls. A renovated strat...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Yao, Qingxin, Lin, Feng, Fan, Xinyuan, Wang, Yanpu, Liu, Ye, Liu, Zhaofei, Jiang, Xingyu, Chen, Peng R., Gao, Yuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261997/
https://ncbi.nlm.nih.gov/pubmed/30487642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07490-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items