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Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs

Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by enzymes, pH or other trigger factors associated w...

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Vydáno v:Molecules
Hlavní autoři: Wang, Yayue, Zhang, Chang, Wu, Haoxing, Feng, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731009/
https://ncbi.nlm.nih.gov/pubmed/33266075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235640
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