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Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs

Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by enzymes, pH or other trigger factors associated w...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wang, Yayue, Zhang, Chang, Wu, Haoxing, Feng, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731009/
https://ncbi.nlm.nih.gov/pubmed/33266075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235640
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