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Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs

Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by enzymes, pH or other trigger factors associated w...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Wang, Yayue, Zhang, Chang, Wu, Haoxing, Feng, Ping
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731009/
https://ncbi.nlm.nih.gov/pubmed/33266075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235640
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