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Activation and Delivery of Tetrazine-Responsive Bioorthogonal Prodrugs

Prodrugs, which remain inert until they are activated under appropriate conditions at the target site, have emerged as an attractive alternative to drugs that lack selectivity and show off-target effects. Prodrugs have traditionally been activated by enzymes, pH or other trigger factors associated w...

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Publicado en:Molecules
Autores principales: Wang, Yayue, Zhang, Chang, Wu, Haoxing, Feng, Ping
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7731009/
https://ncbi.nlm.nih.gov/pubmed/33266075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25235640
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