Llwytho...

Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups

In vivo compatible reactions have a broad range of possible applications in chemical biology and the pharmaceutical sciences. Here we report tetrazines that can be removed by exposure to isonitriles under very mild conditions. Tetrazylmethyl derivatives are easily accessible protecting groups for am...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Tu, Julian, Svatunek, Dennis, Parvez, Saba, Eckvahl, Hannah J., Xu, Minghao, Peterson, Randall T., Houk, K. N., Franzini, Raphael M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7012038/
https://ncbi.nlm.nih.gov/pubmed/32110368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc04649f
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!