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Click to enter: activation of oligo-arginine cell-penetrating peptides by bioorthogonal tetrazine ligations

Cell-penetrating peptides are able to transport a wide variety of cargo across cell membranes. Although promising, they are not often considered for therapeutic purposes as they lack controllable activity and cell selectivity. We have developed an activation strategy based on a split octa-arginine c...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Bode, Saskia A., Timmermans, Suzanne B. P. E., Eising, Selma, van Gemert, Sander P. W., Bonger, Kimberly M., Löwik, Dennis W. P. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340402/
https://ncbi.nlm.nih.gov/pubmed/30746105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04394a
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