Click to enter: activation of oligo-arginine cell-penetrating peptides by bioorthogonal tetrazine ligations

Cell-penetrating peptides are able to transport a wide variety of cargo across cell membranes. Although promising, they are not often considered for therapeutic purposes as they lack controllable activity and cell selectivity. We have developed an activation strategy based on a split octa-arginine c...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Bode, Saskia A., Timmermans, Suzanne B. P. E., Eising, Selma, van Gemert, Sander P. W., Bonger, Kimberly M., Löwik, Dennis W. P. M.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Chemistry
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6340402/
https://ncbi.nlm.nih.gov/pubmed/30746105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04394a
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