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Tetrazine-mediated bioorthogonal prodrug–prodrug activation
The selective and biocompatible activation of prodrugs within complex biological systems remains a key challenge in medical chemistry and chemical biology. Herein we report, for the first time, a dual prodrug activation strategy that fully satisfies the principle of bioorthogonality by the symbiotic...
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| Publicado no: | Chem Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6148199/ https://ncbi.nlm.nih.gov/pubmed/30288239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc02610f |
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