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Biological activity of Pt(IV) prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis
We have recently demonstrated that riboflavin (Rf) functions as unconventional bioorthogonal photocatalyst for the activation of Pt(IV) prodrugs. In this study, we show how the combination of light and Rf with two Pt(IV) prodrugs is a feasible strategy for light-mediated pancreatic cancer cell death...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249213/ https://ncbi.nlm.nih.gov/pubmed/30464209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35655-2 |
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