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Bioorthogonal Chemical Activation of Kinases in Living Systems

[Image: see text] Selective manipulation of protein kinases under living conditions is highly desirable yet extremely challenging, particularly in a gain-of-function fashion. Here we employ our recently developed bioorthogonal cleavage reaction as a general strategy for intracellular activation of i...

詳細記述

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書誌詳細
出版年:ACS Cent Sci
主要な著者: Zhang, Gong, Li, Jie, Xie, Ran, Fan, Xinyuan, Liu, Yanjun, Zheng, Siqi, Ge, Yun, Chen, Peng R.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2016
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882735/
https://ncbi.nlm.nih.gov/pubmed/27280167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00024
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