Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature aging that recapitulates many normal aging characteristics. This disorder is caused by mutation in the LMNA gene leading to the production of progerin which induces misshapen nuclei, cellular senescence, and aging. We previously showe...

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Detaylı Bibliyografya
Yayımlandı:Aging Cell
Asıl Yazarlar: Griveau, Audrey, Wiel, Clotilde, Le Calvé, Benjamin, Ziegler, Dorian V., Djebali, Sophia, Warnier, Marine, Martin, Nadine, Marvel, Jacqueline, Vindrieux, David, Bergo, Martin O., Bernard, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Original Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260922/
https://ncbi.nlm.nih.gov/pubmed/30216637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12835
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