Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature aging that recapitulates many normal aging characteristics. This disorder is caused by mutation in the LMNA gene leading to the production of progerin which induces misshapen nuclei, cellular senescence, and aging. We previously showe...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Griveau, Audrey, Wiel, Clotilde, Le Calvé, Benjamin, Ziegler, Dorian V., Djebali, Sophia, Warnier, Marine, Martin, Nadine, Marvel, Jacqueline, Vindrieux, David, Bergo, Martin O., Bernard, David
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260922/
https://ncbi.nlm.nih.gov/pubmed/30216637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12835
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