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The SCN9A channel and plasma membrane depolarization promote cellular senescence through Rb pathway

Oncogenic signals lead to premature senescence in normal human cells causing a proliferation arrest and the elimination of these defective cells by immune cells. Oncogene‐induced senescence (OIS) prevents aberrant cell division and tumor initiation. In order to identify new regulators of OIS, we per...

詳細記述

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書誌詳細
出版年:Aging Cell
主要な著者: Warnier, Marine, Flaman, Jean‐Michel, Chouabe, Christophe, Wiel, Clotilde, Gras, Baptiste, Griveau, Audrey, Blanc, Elena, Foy, Jean‐Philippe, Mathot, Pauline, Saintigny, Pierre, Van Coppenolle, Fabien, Vindrieux, David, Martin, Nadine, Bernard, David
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5946064/
https://ncbi.nlm.nih.gov/pubmed/29446526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12736
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