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Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence

Cellular senescence response is (i) activated by numerous stresses, (ii) is characterized by a stable proliferation arrest, and (iii) by a set of specific features. Timely regulated senescence is thought to be beneficial, whereas chronic senescence such as during normal or premature aging is deleter...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Collin, Guillaume, Huna, Anda, Warnier, Marine, Flaman, Jean-Michel, Bernard, David
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833687/
https://ncbi.nlm.nih.gov/pubmed/29449545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0300-z
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