Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature aging that recapitulates many normal aging characteristics. This disorder is caused by mutation in the LMNA gene leading to the production of progerin which induces misshapen nuclei, cellular senescence, and aging. We previously showe...

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Bibliografiske detaljer
Udgivet i:Aging Cell
Main Authors: Griveau, Audrey, Wiel, Clotilde, Le Calvé, Benjamin, Ziegler, Dorian V., Djebali, Sophia, Warnier, Marine, Martin, Nadine, Marvel, Jacqueline, Vindrieux, David, Bergo, Martin O., Bernard, David
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260922/
https://ncbi.nlm.nih.gov/pubmed/30216637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12835
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