Targeting the phospholipase A2 receptor ameliorates premature aging phenotypes

Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature aging that recapitulates many normal aging characteristics. This disorder is caused by mutation in the LMNA gene leading to the production of progerin which induces misshapen nuclei, cellular senescence, and aging. We previously showe...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Aging Cell
Päätekijät: Griveau, Audrey, Wiel, Clotilde, Le Calvé, Benjamin, Ziegler, Dorian V., Djebali, Sophia, Warnier, Marine, Martin, Nadine, Marvel, Jacqueline, Vindrieux, David, Bergo, Martin O., Bernard, David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Original Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260922/
https://ncbi.nlm.nih.gov/pubmed/30216637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12835
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