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Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABA(A) receptors

Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABA(A)) receptors, the major inhibitory neurotransmitter-gated ion channels in mammalian central nervous system. Proteosta...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Fu, Yan-Lin, Han, Dong-Yun, Wang, Ya-Juan, Di, Xiao-Jing, Yu, Hai-Bo, Mu, Ting-Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258528/
https://ncbi.nlm.nih.gov/pubmed/30481215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207948
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