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Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABA(A) receptors

Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABA(A)) receptors, the major inhibitory neurotransmitter-gated ion channels in mammalian central nervous system. Proteosta...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Fu, Yan-Lin, Han, Dong-Yun, Wang, Ya-Juan, Di, Xiao-Jing, Yu, Hai-Bo, Mu, Ting-Wei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258528/
https://ncbi.nlm.nih.gov/pubmed/30481215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207948
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