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Remodeling the endoplasmic reticulum proteostasis network restores proteostasis of pathogenic GABA(A) receptors

Biogenesis of membrane proteins is controlled by the protein homeostasis (proteostasis) network. We have been focusing on protein quality control of γ-aminobutyric acid type A (GABA(A)) receptors, the major inhibitory neurotransmitter-gated ion channels in mammalian central nervous system. Proteosta...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Fu, Yan-Lin, Han, Dong-Yun, Wang, Ya-Juan, Di, Xiao-Jing, Yu, Hai-Bo, Mu, Ting-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258528/
https://ncbi.nlm.nih.gov/pubmed/30481215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207948
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