Grp94 Protein Delivers γ-Aminobutyric Acid Type A (GABA(A)) Receptors to Hrd1 Protein-mediated Endoplasmic Reticulum-associated Degradation

Proteostasis maintenance of γ-aminobutyric acid type A (GABA(A)) receptors dictates their function in controlling neuronal inhibition in mammalian central nervous systems. However, as a multisubunit, multispan, integral membrane protein, even wild type subunits of GABA(A) receptors fold and assemble...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Di, Xiao-Jing, Wang, Ya-Juan, Han, Dong-Yun, Fu, Yan-Lin, Duerfeldt, Adam S., Blagg, Brian S. J., Mu, Ting-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850292/
https://ncbi.nlm.nih.gov/pubmed/26945068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.705004
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