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Derlin2 Protein Facilitates HRD1-mediated Retro-translocation of Sonic Hedgehog at the Endoplasmic Reticulum

Endoplasmic reticulum-associated degradation (ERAD) is an important system that eliminates misfolded proteins from the ER. Three derlins have been implicated in this process, but their precise function remains unknown. In this study, we report that although both derlin1 and derlin2 are capable of bi...

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Detalhes bibliográficos
Main Authors: Huang, Chih-Hsiang, Hsiao, Hui-Ting, Chu, Yue-Ru, Ye, Yihong, Chen, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3757197/
https://ncbi.nlm.nih.gov/pubmed/23867461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.455212
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