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Derlin-1 Facilitates the Retro-Translocation of Cholera Toxin
Cholera toxin (CT) intoxicates cells by using its receptor-binding B subunit (CTB) to traffic from the plasma membrane to the endoplasmic reticulum (ER). In this compartment, the catalytic A1 subunit (CTA1) is unfolded by protein disulfide isomerase (PDI) and retro-translocated to the cytosol where...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262961/ https://ncbi.nlm.nih.gov/pubmed/18094046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-08-0755 |
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