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Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation

Cholera toxin travels from the cell surface of affected mammalian cells to the endoplasmic reticulum (ER), where the A1 chain is released and retro-translocated across the ER membrane into the cytosol. We have tested whether, as in other cases, retro-translocation requires poly-ubiquitination. We sh...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Rodighiero, Chiara, Tsai, Billy, Rapoport, Tom A., Lencer, Wayne I.
Формат: Artigo
Язык:Inglês
Опубликовано: 2002
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308323/
https://ncbi.nlm.nih.gov/pubmed/12446567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf239
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