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Role of ubiquitination in retro-translocation of cholera toxin and escape of cytosolic degradation

Cholera toxin travels from the cell surface of affected mammalian cells to the endoplasmic reticulum (ER), where the A1 chain is released and retro-translocated across the ER membrane into the cytosol. We have tested whether, as in other cases, retro-translocation requires poly-ubiquitination. We sh...

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Detalhes bibliográficos
Main Authors: Rodighiero, Chiara, Tsai, Billy, Rapoport, Tom A., Lencer, Wayne I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1308323/
https://ncbi.nlm.nih.gov/pubmed/12446567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf239
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