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Processing and turnover of the Hedgehog protein in the endoplasmic reticulum
The Hedgehog (Hh) signaling pathway has important functions during metazoan development. The Hh ligand is generated from a precursor by self-cleavage, which requires a free cysteine in the C-terminal part of the protein and results in the production of the cholesterol-modified ligand and a C-termina...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Rockefeller University Press
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3051819/ https://ncbi.nlm.nih.gov/pubmed/21357747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008090 |
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